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Séminaire Digiteo - 28 novembre - Ecole Polytechnique - "Computational Structural Biology: Its Birth and Future" par Michael Levitt


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Abstract

Over 40 years ago, Michael Levitt was fortunate to be present at the very start of computation structural biology and indeed computational biology as a whole. His personal account of these historical events have been described before (Levitt, 2001). Here he will focus on the scientific lessons learned from those early times. He will then describe some of the work that has is on-going in his group and focus on how he sees the future of the field.

More information here

 

Biography

Pr. Michael Levitt is leading the Computational Structural Biology Lab  in Stanford University BioX Clark Center. Full professor in the Structural Biology Department, he works on various aspects of Structural Bioinformatics.

Known for his pioneer work in protein-protein folding, he is an expert of energy functions for protein dynamics simulations which made current molecular dynamics experiments possible. He addresses  multiple problems of modern computational biology, from protein structure refinement with experimental data to the relationship between homology and structure.

He was the first to introduce simplified  representation for proteins and also molecular dynamics of nucleic acids  in solution and in vacuo.

Michael Levitt obtained his PhD from Cambridge University in England in  1971. Before coming to Stanford in 1987, he was Postdoctoral fellow with  Shneior Lifson in the Weizmann Institute in Israel, Staff Scientist at  the MRC Laboratory of Molecular Biology in England, visiting scientist  with Francis Crick at the Salk Institute in La Jolla California, and  Professor of Chemical Physics in the Weizmann Institute in Israel.

From 2001 and 2002 resp., he is a Fellow of the Royal Society in United  Kingdom and Member of the US National Academy of Science. He is also  editor for the Journal of Molecular Biology and a member of the Editorial Board of the Proc. Natl. Acad. Sci.


http://csb.stanford.edu/~levitt


 

Informations pratiques :

Lundi 28 Novembre 14h30

Ecole Polytechnique - Amphi Carnot

Route de Saclay

91120 Palaiseau